Cell Culture Proteins

171 products

Recombinant growth factors, cytokines, and matrix proteins for iPSC, organoid, and 3D culture research.

Build your culture workflow with proteins selected for their biological function and documented specifications. Beta LifeScience’s Cell Culture Proteins collection brings together recombinant signaling proteins, culture supplements, and adhesion proteins relevant to stem cell maintenance, directed differentiation, organoid media development, and cell-based research.

Explore FGF2, TGF-β1, Activin A, EGF, R-Spondin-1, Noggin, Wnt-3a, and other proteins used in published culture strategies. Compare species, expression systems, protein formats, purity, endotoxin limits, and available activity data to identify candidates for your protocol.

Quality You Can Evaluate

Purity specifications of ≥95%
Products in this collection list purity specifications of at least 95% by SDS-PAGE. Refer to individual product pages for the analytical method and applicable conditions.

Product-specific endotoxin limits
Select proteins according to the endotoxin requirements of your experiment. Many products list limits of ≤10 EU/mg, with lower limits available for selected products. Specifications vary by product.

Relevant activity information
Available product data describe assays such as cell proliferation, cytokine secretion, pathway-reporter activation, receptor binding, and cell adhesion. Review the assay system and reported activity alongside your intended application.

Details that support reagent selection
Product specifications include expression source, tag, formulation, reconstitution, and storage information. These details help you compare protein formats and plan their integration into your culture workflow.

Explore Proteins by Application

Human iPSC Culture and Expansion

FGF2 and TGF-β signaling are established components of defined human pluripotent stem cell culture strategies. Published systems also incorporate insulin and transferrin as medium components and use defined attachment substrates such as vitronectin or laminin E8 fragments.

Explore our growth factors, medium supplements, and adhesion proteins when selecting components for iPSC culture development. Match the protein construct and formulation to the requirements of your chosen medium and substrate system.

Organoid Culture and Expansion

Organoid media recreate selected signals from the tissue’s stem cell environment. EGF, R-Spondin-1, and Noggin are established components of intestinal organoid culture methods; Wnt-3a is included in selected protocols according to tissue source and culture conditions.

Our collection includes these signaling proteins for researchers developing or adapting organoid media. Factor combinations should be selected for the specific tissue, species, and stage of culture.

Directed Differentiation and Organoid Development

Protein requirements change as cells move from pluripotency toward a defined lineage. Published human intestinal differentiation methods, for example, use Activin A during definitive endoderm induction, followed by FGF4 and Wnt-3a during intestinal specification.

Explore these factors as components of stage-specific differentiation workflows. Protein identity, treatment timing, and compatibility with the complete protocol should guide selection.

3D Culture and Model Development

Three-dimensional models require signals appropriate to their cell composition and biological purpose. Selected growth factors can be evaluated for proliferation, differentiation, or pathway responses in organoids and other 3D systems.

Our collection offers candidates for comparing culture conditions and investigating signaling responses. Requirements vary between models—even between organoids derived from the same tissue—so each factor should be evaluated in the intended system.

Find the Right Protein for Your Workflow

Browse the collection by target and compare the specifications on each product page. For product selection or quotation inquiries, share your cell type, culture format, intended application, and required protein quantity.

Explore Cell Culture Proteins
Request Product Information or a Quote

Application descriptions reflect published uses of the protein targets. Performance of a specific Beta LifeScience product in an iPSC, organoid, or 3D culture system requires evaluation in the intended protocol.

Filters

    171 products
    Carrier effect of rHSA is observed in the cell proliferation in TF-1 human cells treated with Recombinant Human IL-3 in the presence of 25 µg/mL rHSA. The carrier effect due to rHSA does not alter the ED50 in this assay
    Recombinant Mouse Thrombopoietin/Tpo Protein, Active, Low Endotoxin
    • Molecule: THPO;
    • Species: Mouse;
    • Expression system: Mammalian;
    • Sequence: Ser22-Thr356;
    CAT#: BEP-0061UL
    Recombinant Mouse Flt-3 Ligand/FLT3L Protein, Active
    • Molecule: FLT3LG;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Gly27-Arg188;
    CAT#: BEP-0060
    Recombinant Human TGF-beta 1 Protein, Active
    • Molecule: TGFB1;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ala279-Ser390, with an N-terminal Met;
    CAT#: BEP-0059
    Recombinant Human PDGF-AA (2 μg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing 14 kDa (R) and 29 kDa (NR) and purity greater than 98%.
    Recombinant Human PDGF-AA Protein, Active, Low Endotoxin
    • Molecule: PDGFA;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ser87-Thr211;
    CAT#: BEP-0058UL
    Recombinant Human Neurotrophin 3/NT-3 Protein, Active
    • Molecule: NTF3;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Tyr149-Thr257 ;
    CAT#: BEP-0057
    Recombinant Human IL-13 (2 μg/lane) on SDSPAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 15 kDa and purity greater than 98%. and purity greater than 98%.
    Recombinant Human IL-13 Protein, Active, Low Endotoxin
    • Molecule: IL13;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ser19-Asn132, with an N-terminal Met;
    CAT#: BEP-0056UL
    Recombinant Human Heregulin beta1 Protein, Active
    • Molecule: NRG1;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ser177-Glu241;
    CAT#: BEP-0055
    Recombinant Human Epiregulin Protein, Active
    • Molecule: EREG;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Val60-Leu108, with an N-terminal Met;
    CAT#: BEP-0054
    Recombinant Human BMP-4 Protein, Active
    • Molecule: BMP4;
    • Species: Human;
    • Expression system: Mammalian;
    • Sequence: Ser293-Arg408;
    CAT#: BEP-0053
    Recombinant Human BMP-2 Protein, Active
    • Molecule: BMP2;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Gln283-Arg396, with an N-terminal Met;
    CAT#: BEP-0052
    Recombinant Mouse SCF Protein, Active
    • Molecule: KITLG;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Lys26-Ala189, with an N-terminal Met;
    CAT#: BEP-0051
    Recombinant Mouse Noggin/NOG Protein, Active
    • Molecule: NOG;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Gln28-Cys232;
    CAT#: BEP-0050
    Recombinant Human R-Spondin 3/RSPO3 Protein, Active, Low Endotoxin
    • Molecule: RSPO3;
    • Species: Human;
    • Expression system: Mammalian;
    • Sequence: Asn23-His272;
    CAT#: BEP-0049UL
    Recombinant Human/Mouse BDNF Recombinant Human/Mouse BDNF (2 μg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 14 kDa and purity greater than 98%.
    Recombinant Human/Mouse/Rat BDNF Protein, Active, Low Endotoxin
    • Molecule: BDNF;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: His129-Arg247, with an N-terminal Met;
    CAT#: BEP-0048UL
    Recombinant Human/Mouse/Rat Activin A Protein , Active, Low Endotoxin
    • Molecule: INHBA;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Gly311-Ser426;
    CAT#: BEP-0047UL
    Recombinant Human TNF-alpha (2 μg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at about 15 kDa and purity >98%.
    Recombinant Human TNF-alpha Protein, Animal-Free, Active, Low Endotoxin
    • Molecule: TNF;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Val77-Leu233;
    CAT#: BEP-0046UL
    Recombinant Human SCF (2 μg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 15 kDa and purity greater than 98%.
    Recombinant Human SCF Protein, Active, Low Endotoxin
    • Molecule: KITLG;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Glu26-Ala189, with an N-terminal Met;
    CAT#: BEP-0045UL
    Recombinant Human R-Spondin 1/RSPO1 Protein, Active
    • Molecule: RSPO1;
    • Species: Human;
    • Expression system: Mammalian;
    • Sequence: Ser21-Ala263, with an N-terminal Met;
    CAT#: BEP-0044
    Recombinant Human Noggin/NOG Protein, Active
    • Molecule: NOG;
    • Species: Human;
    • Expression system: Mammalian;
    • Sequence: Gnl28-Cys232;
    CAT#: BEP-0043
    Recombinant Human LIF Protein, Active
    • Molecule: LIF;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ser23-Phe202;
    CAT#: BEP-0042
    Recombinant Human IL-7 (2 µg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at ~17 kDa and purity greater than 98%.
    Recombinant Human IL-7 Protein, Active, Low Endotoxin
    • Molecule: IL7;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Asp26-His177, with an N-terminal Met;
    CAT#: BEP-0041
    Recombinant Human IL-2 Protein, Active
    • Molecule: IL2;
    • Species: Human;
    • Expression system: E.coli;
    CAT#: BEP-0040
    Recombinant Mouse IL-6 Protein, Active
    • Molecule: CSF2;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Ala18-Glu144, with an N-terminal Met;
    CAT#: BEP-0039
    Recombinant Mouse IL-6 (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 24 kDa and purity greater than 96%.
    Recombinant Mouse IL-6 Protein, Active, Low Endotoxin
    • Molecule: IL6;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Phe25-Thr211, with an N-terminal Met;
    CAT#: BEP-0038UL
    Recombinant Human FGF-10 (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 20 kDa and purity greater than 95%. Note: Coomassie Blue staining with this protein is weaker than expected.
    Recombinant Human FGF-10 Protein, Active, Low Endotoxin
    • Molecule: FGF10;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Cys37-Ser208, with an N-terminal Met;
    CAT#: BEP-0037UL
    Purified Nuclease (Lane 1: 0.5 μg, Lane 2: 2.0 μg) on SDS-PAGE under reducing conditions. The gel was stained using Coomassie® Blue showing a single band at 29 kDa and purity greater than 98-99%.
    Recombinant DNA/RNA Nuclease, Active, Low Endotoxin
    • Molecule: NucA;
    • Species: Serratia Marcescens;
    • Expression system: E.coli;
    • Sequence: Met1-Asn266;
    CAT#: BEP-0036UL
    Recombinant Mouse TRANCE/RANKL (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 19 kDa and purity greater than 96%.
    Recombinant Mouse TRANCE/RANKL Protein, Active, Low Endotoxin
    • Molecule: TNFSF11;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Ala144-Asp316;
    CAT#: BEP-0035
    Recombinant Mouse TNF-alpha (2 ug/lane) on SDS-AGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 17 kDa and purity greater than 95%.
    Recombinant Mouse TNF-alpha Protein, Active, Low Endotoxin
    • Molecule: TNF;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Leu80-Leu235, with an N-terminal Met;
    CAT#: BEP-0034
    Recombinant Mouse M-CSF/CSF1 Protein (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 26 kDa and purity greater than 97%.
    Recombinant Mouse M-CSF/CSF1 Protein, Active, Low Endotoxin
    • Molecule: CSF1;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Lys33-Glu262, with an N-terminal Met;
    CAT#: BEP-0033UL
    Recombinant Mouse IL-3 (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 15 kDa and purity greater than 95%.
    Recombinant Mouse IL-3 Protein, Active, Low Endotoxin
    • Molecule: IL3;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Asp33-Cys166, with an N-terminal Met;
    CAT#: BEP-0032
    Recombinant Mouse IL-2 (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 17 kDa and purity greater than 97%.
    Recombinant Mouse IL-2 Protein, Active, Low Endotoxin
    • Molecule: IL2;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Ala21-Gln169, with an N-terminal Met;
    CAT#: BEP-0031
    Recombinant Mouse IFN-gamma (2 µg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 11 kDa and purity greater than 95%.
    Recombinant Mouse IFN-gamma Protein, Active, Low Endotoxin
    • Molecule: IFNG;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: His23-Cys155, with an N-terminal Met;
    CAT#: BEP-0030UL
    Recombinant Mouse GM-CSF (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 14 kDa and purity greater than 97%.
    Recombinant Mouse GM-CSF/CSF2 Protein, Active, Low Endotoxin
    • Molecule: CSF2;
    • Species: Mouse;
    • Expression system: E.coli;
    • Sequence: Ala18-Lys141, with an N-terminal Met;
    CAT#: BEP-0029
    Recombinant Human VEGF 165 (2 ug/lane) on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained using Coomassie® Blue showing single bands at 20 kDa (R) and 39 kDa (NR), and purity greater than 98%.
    Recombinant Human VEGF 165 Protein, Active, Low Endotoxin
    • Molecule: VEGFA;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ala27-Arg191;
    CAT#: BEP-0028UL
    Recombinant Human Thrombopoietin/ TPO Protein (2 ug/lane) on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained using Coomassie® Blue showing a single band at 20 kDa and 18 kDa, respectively, and purity greater than 95%.
    Recombinant Human Thrombopoietin/TPO Protein, Active, Low Endotoxin
    • Molecule: THPO;
    • Species: Human;
    • Expression system: Mammalian;
    • Sequence: Ser22-Leu195;
    CAT#: BEP-0027
    Recombinant Human Serum Albumin/HSA Protein, Animal Component-Free (2 ug/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 67 kDa and purity greater than 98%.
    Recombinant Human Serum Albumin/HSA Protein, Animal-Free, Active, Low Endotoxin
    • Molecule: ALB;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Asp25-Leu609;
    CAT#: BEP-0026UL
    Carrier effect of rHSA is observed in the cell proliferation in TF-1 human cells treated with Recombinant Human IL-3 in the presence of 25 µg/mL rHSA. The carrier effect due to rHSA does not alter the ED50 in this assay
    Recombinant Human Serum Albumin/HSA Protein, Active, Low Endotoxin
    • Molecule: ALB;
    • Species: Human;
    • Expression system: Mammalian;
    • Sequence: Asp25-Leu609;
    CAT#: BEP-0025UL
    Recombinant Human PDGF-BB (2 ug/lane) on SDS-AGE under reducing (R) and non-reducing (NR) conditions. The gel was stained using Coomassie® Blue showing single bands at 13 kDa and 28 kDa, respectively, and purity greater than 96%.
    Recombinant Human PDGF-BB Protein, Active, Low Endotoxin
    • Molecule: PDGFB;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ser82-Thr190;
    CAT#: BEP-0024
    Recombinant Human IL-3 (2 µg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 15 kDa and purity greater than 98%.
    Recombinant Human IL-3 Protein, Active, Low Endotoxin
    • Molecule: IL3;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Ala20-Phe152;
    CAT#: BEP-0023UL
    Recombinant Human IL-21 (2 µg/lane) on SDS-PAGE under reducing (R) conditions. The gel was stained using Coomassie® Blue showing a single band at 16 kDa and purity greater than 98%.
    Recombinant Human IL-21 Protein, Active, Low Endotoxin
    • Molecule: IL21;
    • Species: Human;
    • Expression system: E.coli;
    • Sequence: Gln32-Ser162, with an N-terminal Met;
    CAT#: BEP-0022UL

    Cell culture cytokines and growth factors: comparison table

    Which protein to use for which culture, and the formats we stock. Two grades are listed: RUO — research-use-only, bioactivity-tested, 100 µg vials (catalogue prefix BEP); GMP — GMP-grade, ultra-low endotoxin, animal-origin-free, 50 µg to 1 mg vials with bulk on request (prefix BLE). Species, expression host and grade are shown for every format; click a format to open the product page with full specifications.

    Protein Typical use in cell culture Available formats (species · host · grade)
    T, NK and CAR-T cells
    IL-2IL2 T-cell and NK-cell expansion; standard cytokine in CAR-T manufacturing media Human · E. coli · RUO Mouse · E. coli · RUO Human · CHO · GMP
    IL-7IL7 Survival of naïve and memory T cells; used with IL-15 for less-differentiated CAR-T products Human · E. coli · RUO Human · CHO · GMP
    IL-15IL15 NK-cell and memory T-cell expansion; CAR-NK culture Human · E. coli · RUO Human · CHO · GMP · Fc Tag Human · CHO · GMP
    IL-21IL21 Enhances CD8+ T-cell and NK expansion; B-cell differentiation and antibody production Human · E. coli · RUO Human · CHO · GMP · Fc Tag Human · CHO · GMP
    Myeloid and dendritic cells
    IL-4IL4 Monocyte-derived dendritic cells (with GM-CSF); Th2 polarisation Human · E. coli · RUO Mouse · E. coli · RUO Human · CHO · GMP
    GM-CSFCSF2 Dendritic-cell and macrophage differentiation from monocytes or bone marrow Mouse · E. coli · RUO Mouse · E. coli · RUO Mouse · CHO · GMP Human · CHO · GMP
    M-CSFCSF1 Macrophage differentiation (BMDM, monocyte-derived macrophages) Mouse · E. coli · RUO Human · Mammalian · RUO Mouse · CHO · GMP Human · E. coli · GMP
    G-CSFCSF3 Neutrophil differentiation; HSC mobilisation models Human · E. coli · RUO Mouse · CHO · GMP Human · CHO · GMP
    Inflammation and activation
    TNF-αTNF Dendritic-cell maturation, inflammation models, cytotoxicity assays Human · E. coli · RUO Mouse · E. coli · RUO Human · E. coli · GMP Human · CHO · GMP
    IFN-γIFNG Macrophage activation, MHC up-regulation, Th1 and iPSC-derived immune assays Mouse · E. coli · RUO Human · E. coli · RUO Human · E. coli · GMP Human · CHO · GMP
    IL-6IL6 HSC expansion cocktails; hybridoma and plasma-cell culture; Th17 induction Mouse · E. coli · RUO Human · Mammalian · RUO Human · Mammalian · RUO Bovine · E. coli · GMP Human · CHO · GMP
    IL-10IL10 Regulatory T-cell and tolerogenic dendritic-cell assays Human · CHO · GMP
    Hematopoietic cells
    IL-3IL3 Hematopoietic progenitor, mast-cell and basophil culture Mouse · E. coli · RUO Human · E. coli · RUO Human · E. coli · GMP
    SCFKITLG Hematopoietic stem and progenitor expansion; mast-cell culture Mouse · E. coli · RUO Human · E. coli · RUO Human · CHO · GMP
    TPOTHPO HSC maintenance; megakaryocyte and platelet differentiation Mouse · Mammalian · RUO Human · Mammalian · RUO Human · CHO · GMP
    Flt-3 LigandFLT3LG HSC and progenitor expansion; dendritic-cell generation from bone marrow Mouse · E. coli · RUO Human · E. coli · RUO Human · CHO · GMP
    EPOEPO Erythroid differentiation from HSCs and iPSCs Human · Mammalian · RUO Human · CHO · GMP
    Pluripotent and stem cells
    LIFLIF Maintenance of mouse embryonic stem cells in an undifferentiated state Human · E. coli · RUO Human · E. coli · GMP Mouse · HEK293 · GMP Human · CHO · GMP Bovine · E. coli · GMP
    FGF-basic (FGF-2)FGF2 Human iPSC/ESC maintenance; MSC and neural-progenitor expansion Human · E. coli · RUO Fish · Recombinant · GMP Bovine · E. coli · GMP Human · E. coli · GMP Human · E. coli · GMP
    Activin AINHBA Definitive endoderm induction; pluripotency maintenance with FGF-2 Human · E. coli · RUO Human · CHO · GMP
    BMP-4BMP4 Mesoderm, trophoblast and hematopoietic specification from pluripotent cells Human · Mammalian · RUO Human · E. coli · GMP
    BMP-2BMP2 Osteogenic differentiation of MSCs; cardiac mesoderm induction Human · E. coli · RUO Human · E. coli · GMP
    NogginNOG BMP antagonist for neural induction and organoid media Mouse · E. coli · RUO Human · Mammalian · RUO Mouse · CHO · GMP Human · CHO · GMP
    Organoids and epithelia
    R-Spondin 1RSPO1 Wnt agonist in intestinal, hepatic and other organoid media Human · Mammalian · RUO Human · CHO · GMP
    Wnt-3aWNT3A Canonical Wnt activation in organoid and stem-cell culture Human · CHO · GMP · hFc Tag
    EGFEGF Epithelial cells, keratinocytes and most organoid media Human · E. coli · RUO Porcine · CHO · GMP Human · CHO · GMP
    FGF-10FGF10 Lung and airway organoids; epithelial branching models Human · E. coli · RUO Human · E. coli · GMP Human · CHO · GMP
    KGF (FGF-7)FGF7 Keratinocyte and epithelial organoid growth Human · E. coli · RUO Human · CHO · GMP
    HGFHGF Hepatocyte culture and hepatic differentiation of iPSCs Human · CHO · GMP
    Growth factors
    TGF-β1TGFB1 Treg induction, EMT models, chondrogenic differentiation Human · E. coli · RUO Human · HEK293 · GMP Human · CHO · GMP
    VEGF-165VEGFA Endothelial cell culture and angiogenesis assays Human · E. coli · RUO Human · CHO · GMP Human · CHO · GMP
    PDGF-BBPDGFB MSC, fibroblast, pericyte and smooth-muscle cell proliferation Human · E. coli · RUO Human · CHO · GMP
    IGF-1IGF1 Serum-free media supplement; myoblast and chondrocyte culture Human · HEK293 · GMP Human · CHO · GMP Human · CHO · GMP
    InsulinINS Core component of serum-free media (ITS) across cell types Human · Yeast · GMP
    Neural cells
    BDNFBDNF Survival and maturation of neurons from iPSCs and primary tissue Human · E. coli · RUO Human · CHO · GMP
    NGFNGF PC12 differentiation; sensory and sympathetic neuron culture Human · HEK293 · GMP
    GDNFGDNF Dopaminergic and motor-neuron survival and differentiation Human · Mammalian · RUO Human · E. coli · GMP
    Matrix and media proteins
    Laminin-511 / 521 E8LAMA5 Defined, xeno-free coating for iPSC/ESC maintenance Human · HEK293 · GMP Human · HEK293 · GMP · His Tag
    VitronectinVTN Xeno-free coating for pluripotent stem cells in defined media Human · Recombinant · GMP · His Tag
    FibronectinFN1 Attachment coating for primary cells, endothelial and MSC culture Human · HEK293 · GMP Human · HEK293 · GMP · His Tag
    TransferrinTF Iron carrier in serum-free and chemically defined media Human · CHO · GMP Human · CHO · GMP Bovine · CHO · GMP
    Albumin (HSA / BSA)ALB Carrier and stabiliser in serum-free media and cytokine reconstitution Human · E. coli · RUO Human · Mammalian · RUO Bovine · E. coli · RUO Bovine · Mammalian · RUO

    All products are for research use only unless stated otherwise on the product page. Expression host and endotoxin level are listed on each product page; GMP-grade products ship with a lot-specific certificate of analysis.

    Frequently asked questions about cell culture proteins

    What are cell culture proteins and what are they used for?

    Cell culture proteins are recombinant cytokines, growth factors and signalling proteins added to culture medium to control how cells grow, survive, differentiate or stay in a defined state. This collection covers the proteins most often used in cell expansion, differentiation and functional assays, including interleukins, growth factors, Wnt and TGF-beta family proteins, and matrix proteins. All products are for research use only.

    How do I choose between carrier-free and carrier-containing cytokines?

    Carrier-free proteins contain no added carrier protein such as BSA and are the right choice for serum-free, defined or xeno-free culture, mass spectrometry and any application where added protein would interfere. Carrier-containing formulations add a stabiliser that improves shelf life and reduces loss at very low working concentrations. Each product page states the formulation; if you need a specific format, contact us before ordering.

    Are these proteins suitable for stem cell, primary cell and immune cell culture?

    Yes. The proteins in this collection are produced for cell-based work and are tested for bioactivity in a relevant cell assay where applicable. Check the product page for the expression host, bioactivity data and endotoxin level to confirm fit for your cell type and protocol. For sensitive systems such as stem cells and primary cells, choose carrier-free, low-endotoxin lots.

    What quality data is provided with each protein?

    Every product page lists the expression system, tag, purity (typically determined by SDS-PAGE and HPLC), endotoxin level (measured by LAL assay), formulation, activity data where available and storage conditions. Lot-specific certificates of analysis are available on request from inquiry@betalifesci.com.

    How should I reconstitute and store lyophilized proteins?

    Briefly centrifuge the vial, then reconstitute in sterile water or the buffer named on the product page to the recommended concentration, adding liquid gently down the side of the vial rather than vortexing. Store lyophilized protein at -20 °C or below. After reconstitution, add a carrier protein if your application allows, divide into single-use aliquots and freeze at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles.

    Can I order bulk quantities or custom production?

    Yes. Most proteins are available in multiple sizes, and we offer bulk quantities and custom recombinant protein production, including specific expression hosts, tags and formulations. Email inquiry@betalifesci.com with the target, amount and intended application for a quote.

    How fast do in-stock products ship?

    In-stock items usually ship within 1 to 3 business days from our facility in Paoli, Pennsylvania, USA, with worldwide delivery available. Lead times for custom or made-to-order proteins are confirmed with your quote.