Recombinant Human SNRPA Protein

Beta LifeScience SKU/CAT #: BL-4666PS
Recombinant Human SNRPA Protein

Recombinant Human SNRPA Protein

Beta LifeScience SKU/CAT #: BL-4666PS
Catalog No.: BL-4666PS

Product Overview

Tag His
Host Species Human
Synonym U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A, SNRPA, Mud1.
Background SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and is involved in the coupling of splicing and polyadenylation. SNRPA binds stem loop II of U1 snRNA. SNRPA is the first snRNP to interact with pre-mRNA. This interaction is vital for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.
Description SNRPA Human Recombinant expressed in SF9 is a glycosylated, polypeptide chain having a calculated molecular weight of 34 kDa. SNRPA is expressed with a -6x His tag at N-terminus and purified by unique purification methods.
Source Sf9
Purity >95.0% as determined by SDS-PAGE
Endotoxin <1.0 EU per μg by the LAL method.
Formulation SNRPA is supplied in 16mM HEPES buffer pH-7.6, 400mM NaCl and 20% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
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