Recombinant Rhesus Macaque IL5 Protein
Beta LifeScience
SKU/CAT #: BL-0646PS
Recombinant Rhesus Macaque IL5 Protein
Beta LifeScience
SKU/CAT #: BL-0646PS
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Rhesus |
Synonym | Interleukin-5, IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF, IL5. |
Background | The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
Description | IL5 Rhesus Macaque Recombinant expressed in E.Coli is a disulfide-linked homodimeric, non-glycosylated, polypeptide protein containing 2x115aa chains and having a total molecular weight of 26.1kDa.The IL-5 Rhesus Macaque is purified by our unique purification methods. |
Source | E.coli |
AA Sequence | IPTEIPASAL VKETLALLST HRTLLIANET LRIPVPVHKN HQLCTEEIFQ GIGTLESQTV QGGTVERLFK NLSLIKKYIG GQKKKCGEER RRVNQFLDYL QEFLGVMNTE WIIES. |
Purity | >98.0% as determined by HPLC and SDS-PAGE. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Bioactivity | The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 5ng/ml, corresponding to a specific activity of > 2.0 x 105 IU/mg. |
Formulation | Lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH 7.4 and 5% Trehalose. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Lyophilized IL-5 Rhesus Macaque |