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Recombinant Mouse ERN1 (IRE1) Protein

Cat No.: BL-0001SG
Description Related products
tag GST
host species Mouse
accession NM_023913
synonym Ire1a; Ire1p; C85377; AI225830; Ire1alpha; 9030414B18Rik
background ERN1 or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals. ERN1 controls IRE1 proteolysis in mammalian cells (1). The activation of ERN1 through oligomerization expands the mechanistic repertoire of kinase-based signaling receptors. ERNI has a critical function in extraembryonic cells that is essential for fetal viability (2).
description Recombinant mouse ERN1 (IRE1) (469-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
source Sf9 insect cells
AA sequence 469a.a.-end
molecular weight 87 kDa
purity For specific purity information on a given lot, see related COA.
endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
bioactivity Active
formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
stability The recombinant protein is stable for up to 12 months at -70℃
usage For Research Use Only
storage Recombinant Mouse ERN1 (IRE1) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Cat No. Product Name Source Detail Inquiry
BL-0060SG Recombinant Human ERN1 (R727A) Protein Sf9 insect cells
BL-0061SG Recombinant Human ERN1 (R728A) Protein Sf9 insect cells
BL-0458SG Recombinant Human ERN1 (IRE1) Protein Sf9 insect cells
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