Recombinant Mouse B7-1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0309
Recombinant Mouse B7-1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0309
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Mouse |
Accession | Q00609 |
Synonym | CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, CD80 molecule |
Background | Cluster of differentiation 80 (also CD80 and B7-1) is a B7, type I membrane protein[5] that is in the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is closely related to CD86, another B7 protein (B7-2), and often works in tandem, binding to the same receptors to prime T cells. |
Description | A DNA sequence encoding the mouse CD80 (Q00609-1) extracellular domain (Met 1-Lys 245) was fused with the Fc region of human IgG1 at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Val 38 |
AA Sequence | Met 1-Lys 245 |
Molecular Weight | The recombinant mouse CD80 consists of 449 amino acids and has a predicted molecular mass of 50.7 kDa. |
Purity | Greater than 90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | 1. Measured by its binding ability in a functional ELISA.2. Immobilized human CTLA4 at 10 ug/mL (100 ul/well) can bind mouse CD80-Fc, The EC50 of mouse CD80-Fc is 28 ng/mL. |
Formulation | Lyophilized from sterile PBS, pH 7.4 |
Stability | Recombinnat Proteins are stable for up to 1 year from date of receipt at -70°C |
Usage | For Research Use Only |
Storage | Store recombinant protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |