Recombinant Xenopus UBE2D2 (UBC4) Protein
Beta LifeScience
SKU/CAT #: BL-0120SG
Recombinant Xenopus UBE2D2 (UBC4) Protein
Beta LifeScience
SKU/CAT #: BL-0120SG
Catalog No.: BL-0120SG
Product Overview
| Tag | His |
| Host Species | Xenopus |
| Accession | NM_001093036 |
| Synonym | UBC4; PUBC1; UBC4/5; UBCH5B; E2(17)KB2 |
| Background | UBE2D2(UBC4) Protein or ubiquitin-conjugating enzyme E2D2 is a member of the E2 ubiquitin-conjugating enzyme family which functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. UBE2D2 specifically ubiquitinates E6AP and in vivo inhibition of UBE2D2 can lead to inhibition of E6-stimulated p53 degradation (1). UBE2D2 could conjugate ubiquitin to target proteins in an E6AP-dependent manner. |
| Description | Recombinant full-length Xenopus UBE2D2 was produced in E. coli system, fused with a His tag at N-terminus. |
| Source | E.coli |
| AA Sequence | Full Length |
| Molecular Weight | 17 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Xenopus UBE2D2 (UBC4) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
