Recombinant Xenopus UBE2D2 (UBC4) Protein

Beta LifeScience SKU/CAT #: BL-0120SG
Recombinant Xenopus UBE2D2 (UBC4) Protein

Recombinant Xenopus UBE2D2 (UBC4) Protein

Beta LifeScience SKU/CAT #: BL-0120SG
Catalog No.: BL-0120SG

Product Overview

Tag His
Host Species Xenopus
Accession NM_001093036
Synonym UBC4; PUBC1; UBC4/5; UBCH5B; E2(17)KB2
Background UBE2D2(UBC4) Protein or ubiquitin-conjugating enzyme E2D2 is a member of the E2 ubiquitin-conjugating enzyme family which functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. UBE2D2 specifically ubiquitinates E6AP and in vivo inhibition of UBE2D2 can lead to inhibition of E6-stimulated p53 degradation (1). UBE2D2 could conjugate ubiquitin to target proteins in an E6AP-dependent manner.
Description Recombinant full-length Xenopus UBE2D2 was produced in E. coli system, fused with a His tag at N-terminus.
Source E.coli
AA Sequence Full Length
Molecular Weight 17 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Xenopus UBE2D2 (UBC4) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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