Recombinant Rhesus LAMP3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3135
Recombinant Rhesus LAMP3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3135
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Rhesus |
Accession | Q8MJJ2 |
Synonym | LAMP3 |
Background | Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD28, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm18, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. |
Description | A DNA sequence encoding the rhesus LAMP3 (Q8MJJ2) (Lys28-Thr381) was expressed with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Lys 28 |
AA Sequence | Lys28-Thr381 |
Molecular Weight | The recombinant rhesus LAMP3 comprises 365 a.a. and has a calculated molecular mass of 39 KDa. |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, PH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |