Recombinant Rat IL2 Protein
Beta LifeScience
SKU/CAT #: BL-0597PS
Recombinant Rat IL2 Protein
Beta LifeScience
SKU/CAT #: BL-0597PS
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | N/A |
Host Species | Rat |
Synonym | T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2. |
Background | IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
Description | Interleukin-2 Rat Recombinant expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 135a.a. and having a molecular weight of 16kDa.The IL-2 is purified by unique purification methods. |
Source | E.coli |
AA Sequence | APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ. |
Purity | >97.0% as determined by SDS-PAGE and HPLC. |
Endotoxin | <1.0 EU per μg by the LAL method. |
Bioactivity | The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is less than 0.2ng/ml, corresponding to a Specific Activity of 5,000,000IU/mg. |
Formulation | The IL-2 solution contains 0.2µm filtered solution in 20mM PB pH3.5 and 30% Glycerol. |
Stability | Recombinant protein is stable for 12 months at -70°C |
Usage | For Research Use Only |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |