Recombinant Rat CLEC5A Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1317
Recombinant Rat CLEC5A Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1317
Catalog No.: BLPSN-1317
Product Overview
| Tag | His |
| Host Species | Rat |
| Accession | F7GAV1 |
| Background | CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. |
| Description | A DNA sequence encoding the rat CLEC5A (F7GAV1) (Val30-Lys190) was expressed with a His tag at the N-terminus. |
| Source | HEK293 |
| Predicted N Terminal | His |
| AA Sequence | Val30-Lys190 |
| Molecular Weight | The recombinant rat CLEC5A comprises 181 a.a. and has a predicted molecular mass of 20.6 kDa. The apparent molecular mass of the protein is approximately 36 kDa in SDS-PAGE under reducing conditions. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
