Recombinant Rat CLEC5A Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1317
Recombinant Rat CLEC5A Protein (His Tag)

Recombinant Rat CLEC5A Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-1317
Catalog No.: BLPSN-1317

Product Overview

Tag His
Host Species Rat
Accession F7GAV1
Background CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
Description A DNA sequence encoding the rat CLEC5A (F7GAV1) (Val30-Lys190) was expressed with a His tag at the N-terminus.
Source HEK293
Predicted N Terminal His
AA Sequence Val30-Lys190
Molecular Weight The recombinant rat CLEC5A comprises 181 a.a. and has a predicted molecular mass of 20.6 kDa. The apparent molecular mass of the protein is approximately 36 kDa in SDS-PAGE under reducing conditions.
Purity >95% as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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