Name: Recombinant Rat C-Reactive Protein Protein (His Tag)
Brand: Beta LifeScience
SKU: BLPSN-1417
Availability: InStock

Recombinant Rat C-Reactive Protein Protein (His Tag)

Catalog No.: BLPSN-1417

Product Overview

Tag	His
Host Species	Rat
Accession	NP_058792.1
Background	C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.
Description	A DNA sequence encoding the rat CRP (NP_058792.1) extracellular domain (Met 1-Ser 230) was fused with a His tag at the C-terminus.
Source	HEK293
Predicted N Terminal	Glu 21
AA Sequence	Met 1-Ser 230
Molecular Weight	The recombinant rat CRP comprises 221 a.a. and predicts a molecular mass of 24.6 kDa. The apparent molecular mass of the rat CRP is approximately 30 kDa in SDS-PAGE under reducing conditions.
Purity	>97% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity	Please contact us for detailed information
Formulation	Lyophilized from sterile PBS, pH 7.4.
Stability	The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage	For Research Use Only
Storage	Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.