Recombinant Mouse SDF2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4177
Recombinant Mouse SDF2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4177
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Mouse |
Accession | Q9DCT5 |
Synonym | AI853825 |
Background | Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from themousestromal cell lineST2 as asecretory protein. The amino acid sequence deduced from themurineclone and thehumanhomologare conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those ofyeastdolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value. |
Description | A DNA sequence encoding the mouse SDF2 (Q9DCT5) (Met 1-Leu 211) was expressed,with a C-terminal His tag. |
Source | Baculovirus-Insect Cells |
Predicted N Terminal | Ser 19 |
AA Sequence | Met 1-Leu 211 |
Molecular Weight | The secreted recombinant mouse SDF2 consists of 203 a.a. and has a calculated molecular mass of 22.8 kDa. It migrates as an approximately 27 kDa band in SDS-PAGE under reducing conditions. |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Target Details
Subcellular Location | Secreted. |
Database References | |
Tissue Specificity | Ubiquitously expressed with highest expression in liver and kidney. |
Gene Functions References
- Comparing the amino acid sequence and predicted 3D structure with other Sdf2-like proteins we suggest a role of mouse Sdf2 in the Unfolded Protein Response and ER-stress, similar to that of Sdf2l1 from human and mouse and SDF2-like from Arabidopsis PMID: 24878610