Recombinant Mouse P-selectin Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0194NP
Recombinant Mouse P-selectin Protein (Fc Tag)

Recombinant Mouse P-selectin Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0194NP
Catalog No.: BL-0194NP

Product Overview

Tag Fc
Host Species Mouse
Accession Q01102
Synonym P-selectin P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; PADGEM
Background P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells. It induced expression in lung, liver, kidney and heart after endotoxin treatment. Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. it also mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P-selectin interacts with SNX17, PSGL1/SEPL, PODXL2, mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.
Description Recombinant Mouse P-selectin is expressed by our Mammalian expression system and the target gene encoding Trp42-­Ala709 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Trp42-­Ala709
Purity >90% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Mouse P-selectin Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Mouse P-selectin protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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