Recombinant Mouse P-selectin Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0194NP
Recombinant Mouse P-selectin Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0194NP
Catalog No.: BL-0194NP
Product Overview
| Tag | Fc |
| Host Species | Mouse |
| Accession | Q01102 |
| Synonym | P-selectin P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; PADGEM |
| Background | P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells. It induced expression in lung, liver, kidney and heart after endotoxin treatment. Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. it also mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P-selectin interacts with SNX17, PSGL1/SEPL, PODXL2, mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1. |
| Description | Recombinant Mouse P-selectin is expressed by our Mammalian expression system and the target gene encoding Trp42-Ala709 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Trp42-Ala709 |
| Purity | >90% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Recombinant Mouse P-selectin Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Mouse P-selectin protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
