Recombinant Mouse NgR Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0135NP
Recombinant Mouse NgR Protein (Fc Tag)

Recombinant Mouse NgR Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0135NP
Catalog No.: BL-0135NP

Product Overview

Tag Fc
Host Species Mouse
Accession Q99PI8
Synonym NgR Reticulon-4 Receptor; Nogo Receptor; NgR; Nogo-66 Receptor; RTN4R; NOGOR
Background Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
Description Recombinant Mouse Nogo-66 Receptor/Reticulon 4 Receptor is expressed by our Mammalian expression system and the target gene encoding Cys27-Ser447 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Cys27-Ser447
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Mouse NgR Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Mouse NgR protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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