Recombinant Mouse LMIR1 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0108NP
Recombinant Mouse LMIR1 Protein (Fc Tag)

Recombinant Mouse LMIR1 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0108NP
Catalog No.: BL-0108NP

Product Overview

Tag Fc
Host Species Mouse
Accession Q6SJQ0
Synonym LMIR1 CD300a;CD300a antigen;CMRF35H9; CD300a molecule; leukocyte immunoglobulin-like receptor;CD300 antigen-like family member A; CMRF35-like molecule 8;NK inhibitory receptor; Immunoglobulin superfamily member 12; IRp60;Inhibitory receptor protein 60; CLM8; CMRF-35H; IGSF12; IRC1; IRC2; LMIR1;CLM-8;MAIR-I
Background LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.
Description Recombinant Mouse Leukocyte mono-Ig-like receptor 1 is expressed by our Mammalian expression system and the target gene encoding Leu28-Arg183 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Leu28-Arg183
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Mouse LMIR1 Protein was lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Mouse LMIR1 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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