Recombinant Mouse GAPDH Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2200
Recombinant Mouse GAPDH Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2200
Catalog No.: BLPSN-2200
Product Overview
| Tag | His |
| Host Species | Mouse |
| Accession | P16858 |
| Synonym | Gapd |
| Background | Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions. |
| Description | A DNA sequence encoding the mouse GAPDH (P16858) (Met1-Glu333) was expressed with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | His |
| AA Sequence | Met1-Glu333 |
| Molecular Weight | The recombinant mouse GAPDH consists of 349 a.a. and predicts a molecular mass of 37.9 KDa. It migrates as an approximately 38 KDa band in SDS-PAGE under reducing conditions due to glycosylation. |
| Purity | >85% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 50 mM Tris, 200 mM Arg, 10% gLycerol.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
