Recombinant Mouse FGFR2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2068
Recombinant Mouse FGFR2 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-2068
Product Overview
| Tag | His |
| Host Species | Mouse |
| Accession | NP_963895.2 |
| Synonym | FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, fibroblast growth factor receptor 2 |
| Background | Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene residing on chromosome 10. FGFR2 is a receptor for fibroblast growth factor.FGFR2 has important roles in embryonic development and tissue repair, especially bone and blood vessels. Like the other members of the fibroblast growth factor receptor family, these receptors signal by binding to their ligand and dimerisation (pairing of receptors), which causes the tyrosine kinase domains to initiate a cascade of intracellular signals. FGFR2 has two naturally occurring isoforms, FGFR2IIIb and FGFR2IIIc, created by splicing of the third immunoglobulin-like domain. FGFR2IIIb is predominantly found in ectoderm derived tissues and endothelial organ lining, i.e. skin and internal organs |
| Description | A DNA sequence encoding the mouse FGFR2 (Met1-Glu263) was expressed with a C-terminal His tag. |
| Source | HEK293 |
| Predicted N Terminal | Arg 22 |
| AA Sequence | Met1-Glu263 |
| Molecular Weight | The recombinant mouse FGFR2 comprises 253 amino acids and has a predicted molecular mass of 28.5 kDa. The apparent molecular mass of the protein is approximately 52.3 kDa in SDS-PAGE under reducing conditions. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Please contact us for detailed information |
| Formulation | Recombinant Mouse FGFR2 Protein (His Tag) was lyophilized from sterile PBS, pH 7.4. |
| Stability | Recombinant Mouse FGFR2 protein is stable up to 1 year at -70°C |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
