Recombinant Mouse Fas Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0164NP
Recombinant Mouse Fas Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0164NP
Catalog No.: BL-0164NP
Product Overview
| Tag | Fc |
| Host Species | Mouse |
| Accession | P25446 |
| Synonym | Fas Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD95;Fas;TNFRSF6 |
| Background | Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected in various tissues including thymus, liver, lung, heart, and adult ovary. As a receptor for TNFSF6/FASLG, The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
| Description | Recombinant Mouse Apoptosis-mediating Surface Antigen FAS is expressed by our Mammalian expression system and the target gene encoding Gln22-Arg169 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Gln22-Arg169 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Recombinant Mouse Fas Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Mouse Fas protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
