Recombinant Mouse EphA3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1804
Recombinant Mouse EphA3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1804
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Mouse |
Accession | NP_034270.1 |
Synonym | AW492086, Cek4, End3, ETK1, Hek, Hek4, Mek4, Tyro4 |
Background | EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune CheckpointImmunotherapyCancer ImmunotherapyTargeted Therapy |
Description | A DNA sequence encoding the mouse EPHA3 (NP_034270.1) (Met1-His541) was expressed with a C-terminal His tag. |
Source | HEK293 |
Predicted N Terminal | Glu 21 |
AA Sequence | Met1-His541 |
Molecular Weight | The recombinant mouse EPHA3 comprises 532 a.a. and has a predicted molecular mass of 60.2 kDa. |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | 1. Measured by its binding ability in a functional ELISA.2. Immobilized mouse EPHA3-His at 10 ug/mL (100 uL/well) can bind mouse EFNA5-Fc. The EC50 of mouse EFNA5-Fc is 4.9-11.4ng/mL. |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |