Recombinant Mouse Dtk Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0116NP
Recombinant Mouse Dtk Protein (Fc Tag)

Recombinant Mouse Dtk Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0116NP
Catalog No.: BL-0116NP

Product Overview

Tag Fc
Host Species Mouse
Accession P55144
Synonym Dtk Tyrosine-protein kinase receptor TYRO3; Etk2; tyro3; TK19-2; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kinase TIF
Background Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterized for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.
Description Recombinant Mouse Developmental Tyrosine Kinase/Tyrosine Protein Kinase Receptor TYRO3 is expressed by our Mammalian expression system and the target gene encoding Ala31-Ser418 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Ala31-Ser418
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Mouse Dtk Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Mouse Dtk protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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