Recombinant Mouse CEL Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1217
Recombinant Mouse CEL Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-1217
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Mouse |
Accession | NP_034015.1 |
Synonym | 1810036E18Rik, BAL |
Background | CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL cause maturity-onset diabetes of the young as well as pancreatic exocrine dysfunction. The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or -stimulated lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary glands. The human CEL gene resides on chromosome 9q34.3 and contains a variable number of tandem repeats (VNTR) region that encodes a mucin-like protein tail. |
Description | A DNA sequence encoding the mouse CEL (NP_034015.1) (Met1-Leu534) was expressed with a C-terminal His tag. |
Source | Baculovirus-Insect Cells |
Predicted N Terminal | Ala 21 |
AA Sequence | Met1-Leu534 |
Molecular Weight | The recombinant mouse CEL comprises 525 a.a. and has a predicted molecular mass of 58.2 kDa. The apparent molecular mass of the protein is approximately 133.9 and 59.1 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Purity | (27.3+65.4)% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |