Recombinant Mouse CAMKIV Protein
Beta LifeScience
SKU/CAT #: BLPSN-0536
Recombinant Mouse CAMKIV Protein
Beta LifeScience
SKU/CAT #: BLPSN-0536
Catalog No.: BLPSN-0536
Product Overview
| Tag | N/A |
| Host Species | Mouse |
| Accession | P08414 |
| Synonym | A430110E23Rik, AI666733, CaMKIV, CaMKIV/Gr, D18Bwg0362e |
| Background | Ca2+/ calmodulin-dependent protein kinase 4 (CAMK-…£) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme implicated in the phophoinositide amplification cascade. Ca2+/calmodulin dependent protein kinase (CAMK) can be activated by the introcellular increased Ca2+ and then apt to combine with the target protein. Ca2+/ calmodulin-dependent protein kinase 4 (CAMK-…£) is a multifunctional CaM-dependent kinase protein with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. All of the isforms of this family, including myosin light chain kinase, phosphorylase kinase, CaMK1, CaMK-…¢ and CaMK-…£ have EF-hand structure. |
| Description | A DNA sequence encoding the mouse CAMK4(P08414) (Met1-Tyr469) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus. |
| Source | Baculovirus-Insect Cells |
| Predicted N Terminal | Gly |
| AA Sequence | Met1-Tyr469 |
| Molecular Weight | The recombinant mouse CAMK4 consists of 471 a.a. and predicts a molecular mass of 52.7 KDa. It migrates as an approximately 55 KDa band in SDS-PAGE under reducing conditions. |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Formulation | Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
