Recombinant Mouse BMP2K Protein

Beta LifeScience SKU/CAT #: BL-0019SG
Recombinant Mouse BMP2K Protein

Recombinant Mouse BMP2K Protein

Beta LifeScience SKU/CAT #: BL-0019SG
Catalog No.: BL-0019SG

Product Overview

Tag GST
Host Species Mouse
Accession NM_080708
Synonym BIKE; 4933417M22Rik; AA673486; AV128808
Background BMP2K or Bone morphogenic protein 2 inducible kinase is the human homolog of mouse BMP-2-inducible kinase which plays a key role in skeletal development and patterning. BMP2K is a serine/threonine protein kinase which contains a nuclear localization signal and plays a regulatory role in attenuating the program of osteoblast differentiation. BMP2K gene is strongly correlated with high myopia and may contribute to a genetic risk factor for high degrees of myopic pathogenesis (1). BMP-2 expression is suppressed by an EP4 receptor antagonist and PGE2 produced by COX-2 increases BMP-2 expression via binding the EP4 receptor (2).
Description Recombinant mouse BMP2K (1-422) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 1-422
Molecular Weight 70 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Mouse BMP2K Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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