Recombinant Mouse Allergin 1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0152
Recombinant Mouse Allergin 1 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-0152
Catalog No.: BLPSN-0152
Product Overview
| Tag | Fc |
| Host Species | Mouse |
| Accession | NP_001028607.1 |
| Synonym | Allergin-1, Gm885, Mca32 |
| Background | Cell surface immunoreceptor MILR1 (mast cell immunoglobulin-like receptor 1; synonyms, Allergin-1) has been shown to suppress immunoglobulin E (IgE)-mediated, mast cell-dependent responses in both mice and humans.The C allele of rs65423 was associated with increased expression of MILR1, which was in accordance with the results of expression quantitative trait loci analysis using human leukocytes. The rs65423 polymorphism affects MILR1 expression levels in humans, leading to a susceptibility to producing specific IgE antibodies against common allergens. |
| Description | A DNA sequence encoding the mouse MILR1 (NP_001028607.1) (Met1-Ser150) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Source | HEK293 |
| Predicted N Terminal | Ile 34 |
| AA Sequence | Met1-Ser150 |
| Molecular Weight | The recombinant mouse MILR1 consists of 355 a.a. and predicts a molecular mass of 39.8 kDa. |
| Purity | >95% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4.. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
