Recombinant Mouse 4--­1BB Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0244NP
Recombinant Mouse 4--­1BB Protein (Fc Tag)

Recombinant Mouse 4--­1BB Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0244NP
Catalog No.: BL-0244NP

Product Overview

Tag Fc
Host Species Mouse
Accession P20334
Synonym 4-­1BB Secreted CD137 antigen ;Tumor necrosis factor receptor superfamily member 9 ;Tnfrsf9
Background Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Description Recombinant Mouse 4-1BB ligand receptor is expressed by our Mammalian expression system and the target gene encoding Val24-Leu187 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Val24-Leu187
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Mouse 4-­1BB Protein was supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Usage For Research Use Only
Storage Mouse 4-­1BB protein should be stored at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
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