Recombinant Human VSIG4 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0070NP
Recombinant Human VSIG4 Protein (Fc Tag)

Recombinant Human VSIG4 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0070NP
Catalog No.: BL-0070NP

Product Overview

Tag Fc
Host Species Human
Accession Q9Y279
Synonym VSIG4 V-set and immunoglobulin domain-containing protein 4; VSIG4;Protein Z39Ig;Z39IG;CRIg
Background V-set and immunoglobulin domain-containing protein 4(VSIG4) is a transmembrane protein contains a signal peptide, a V-type Ig-like domain, a C2-type Ig-like domain, several potential O-glycosylation sites, and an intracellular domain with 2 potential phosphorylation sites and is structurally related to the B7 family of immune regulatory proteins. This protein is also a receptor for the complement component 3 fragments C3b and iC3b.The main function is strong negative regulator of T-cell proliferation and IL2 production and it is also potent inhibitor of the alternative complement pathway convertases. It abundantly expressed in several fetal tissues such as adult tissues, highest expression in lung and placenta and it also expressed in resting macrophages.
Description Recombinant Human V-Set and Immunoglobulin Domain-Containing Protein 4 is expressed by our Mammalian expression system and the target gene encoding Arg20-Val284 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Arg20-Val284
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human VSIG4 Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human VSIG4 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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