Recombinant Human UNC5B Protein (ECD, Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-4738
Recombinant Human UNC5B Protein (ECD, Fc Tag)

Recombinant Human UNC5B Protein (ECD, Fc Tag)

Beta LifeScience SKU/CAT #: BLPSN-4738
Catalog No.: BLPSN-4738

Product Overview

Tag Fc
Host Species Human
Accession NP_734465.2
Synonym p53RDL1, UNC5H2
Background The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. In addition, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.
Description A DNA sequence encoding the human UNC5B (NP_734465.2) (Met1-Pro363) was expressed with the Fc region of human IgG1 at the C-terminus.
Source HEK293
Predicted N Terminal Gly 27
AA Sequence Met1-Pro363
Molecular Weight The recombinant human UNC5B consists 578 a.a. and predicts a molecular mass of 64.8 kDa.
Purity >(77.3+10.2+ 4.2)% as determined by SDS-PAGE.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4..
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recently viewed