Recombinant Human ULBP-2 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0013NP
Recombinant Human ULBP-2 Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0013NP
Catalog No.: BL-0013NP
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | Q9BZM5 |
| Synonym | ULBP-2 NKG2D Ligand 2; N2DL-2; NKG2DL2; ALCAN-Alpha; Retinoic Acid Early Transcript 1H; UL16-Binding Protein 2; ULBP2; N2DL2; RAET1H |
| Background | NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance. |
| Description | Recombinant Human UL16 Binding Protein-2/NKG2D ligand 2 is expressed by our Mammalian expression system and the target gene encoding Gly26-Ser217 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Gly26-Ser217 |
| Purity | >90% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Bioactivity | Measured by its ability to bind Human ULBP-2 in functional ELISA. The ED50 for this effect is less than 30 ug/ml. |
| Formulation | Recombinant Human ULBP-2 Protein was lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Human ULBP-2 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
