Recombinant Human UBE2D1 (UBCH5A) Protein

Beta LifeScience SKU/CAT #: BL-0119SG
Recombinant Human UBE2D1 (UBCH5A) Protein

Recombinant Human UBE2D1 (UBCH5A) Protein

Beta LifeScience SKU/CAT #: BL-0119SG
Catalog No.: BL-0119SG

Product Overview

Tag His
Host Species Human
Accession NM_003338
Synonym E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
Background UBE2D1 (UBCH5A) or ubiquitin-conjugating enzyme E2D1 is a member of the E2 ubiquitin-conjugating enzyme family which is closely related to a stimulator of iron transport (SFT). UBE2D1 is significantly upregulated in livers of iron-overloaded patients with hereditary hemochromatosis. UBE2D1 also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF-1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Description Recombinant full-length human UBE2D1 was produced in E. coli system, fused with a His tag at N-terminus.
Source E.coli
AA Sequence Full Length
Molecular Weight 17 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human UBE2D1 (UBCH5A) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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