Recombinant Human UBE2D1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4712
Recombinant Human UBE2D1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4712
Catalog No.: BLPSN-4712
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | P51668 |
| Synonym | E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A |
| Background | Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells. |
| Description | A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed, with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met |
| AA Sequence | Ala 2-Met 147 |
| Molecular Weight | The recombinant human UBE2D1 consisting of 161 a.a. and has a calculated molecular mass of 18.3 kDa. It migrates as an approximately16 kDa band in SDS-PAGE under reducing conditions. |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile 25mM Tris, 100mM NaCl, 20% glycerol, 0.05% Tween. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
