Recombinant Human UBA1 (UBE1) Protein

Beta LifeScience SKU/CAT #: BL-0160SG
Recombinant Human UBA1 (UBE1) Protein

Recombinant Human UBA1 (UBE1) Protein

Beta LifeScience SKU/CAT #: BL-0160SG
Catalog No.: BL-0160SG

Product Overview

Tag GST
Host Species Human
Accession NM_003334
Synonym UBE1, CTD-2522E6.1, A1S9, A1S9T, A1ST, AMCX1, GXP1, POC20, SMAX2, UBA1A, UBE1X
Background Ubiquitin-activating enzyme 1 (UBA1) catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Posttranslational modification by ubiquitin or ubiquitin-like proteins regulates numerous processes, including cell division, immune responses and embryonic development.
Description Full-length recombinant human UBA1 was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence Full Length
Molecular Weight 145 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human UBA1 (UBE1) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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