Recombinant Human TSC22D1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4687
Recombinant Human TSC22D1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4687
Catalog No.: BLPSN-4687
Product Overview
| Tag | His |
| Host Species | Human |
| Accession | Q15714 |
| Synonym | Ptg-2, TGFB1I4, TSC22 |
| Background | TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor which negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity. |
| Description | A DNA sequence encoding the human TSC22D1 isoform 2 (Q15714-2) (Met 1-Ala 144) was expressed, with a His tag at the N-terminus. |
| Source | E.coli |
| Predicted N Terminal | Met |
| AA Sequence | Met 1-Ala 144 |
| Molecular Weight | The recombinant human TSC22D1 consisting of 155 a.a. and has a calculated molecular mass of 17.2 kDa. It migrates as an 20 kDa band in SDS-PAGE under reducing conditions as predicted. |
| Purity | >92% as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Bioactivity | Please contact us for detailed information |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
| Usage | For Research Use Only |
| Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
