Recombinant Human TSC22D1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-4687
Recombinant Human TSC22D1 Protein (His Tag)

Recombinant Human TSC22D1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BLPSN-4687
Catalog No.: BLPSN-4687

Product Overview

Tag His
Host Species Human
Accession Q15714
Synonym Ptg-2, TGFB1I4, TSC22
Background TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor which negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.
Description A DNA sequence encoding the human TSC22D1 isoform 2 (Q15714-2) (Met 1-Ala 144) was expressed, with a His tag at the N-terminus.
Source E.coli
Predicted N Terminal Met
AA Sequence Met 1-Ala 144
Molecular Weight The recombinant human TSC22D1 consisting of 155 a.a. and has a calculated molecular mass of 17.2 kDa. It migrates as an 20 kDa band in SDS-PAGE under reducing conditions as predicted.
Purity >92% as determined by SDS-PAGE
Endotoxin Please contact us for more information.
Bioactivity Please contact us for detailed information
Formulation Lyophilized from sterile PBS, pH 7.4.
Stability The recombinant proteins are stable for up to 1 year from date of receipt at -70°C.
Usage For Research Use Only
Storage Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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