Recombinant Human TGFBR2 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0043NP
Recombinant Human TGFBR2 Protein (Fc Tag)

Recombinant Human TGFBR2 Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0043NP
Catalog No.: BL-0043NP

Product Overview

Tag Fc
Host Species Human
Accession P37173
Synonym TGFBR2 TGF-beta receptor type-2; TGF-beta type II receptor;TGFBR2; Transforming growth factor-beta receptor type II
Background TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.
Description Recombinant Human Transforming Growth Factor-beta Receptor Type II is expressed by our Mammalian expression system and the target gene encoding Thr23-Asp159 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Thr23-Asp159
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human TGFBR2 Protein was lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human TGFBR2 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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