Recombinant Human TGFBR2 Protein
Beta LifeScience
SKU/CAT #: BL-0349SG
Recombinant Human TGFBR2 Protein
Beta LifeScience
SKU/CAT #: BL-0349SG
Catalog No.: BL-0349SG
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | NM_003242 |
| Synonym | AAT3, FAA3, MFS2, RIIC, HNPCC6, TGFR-2, TGFbeta-RII, TAAD2 |
| Background | TGFbetaR2 is a member of the TGFbeta receptor subfamily and is a ser/thr protein kinase. TGFbetaR2-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses (1). The TGFbetaR2 receptor transmits signals from the cell surface to the nucleus and provides instructions for making transforming growth factor (TGF)-beta type II receptor. Mutations in TGFbetaR2 gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors (2). |
| Description | Recombinant human TGFbetaR2 (190-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. This protein is purified with our unique purification methods. |
| Source | Sf9 insect cells |
| AA Sequence | 190a.a.-end |
| Molecular Weight | ~68 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Human TGFBR2 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
