Recombinant Human TCF4 Protein

Beta LifeScience SKU/CAT #: BL-4273PS
Recombinant Human TCF4 Protein

Recombinant Human TCF4 Protein

Beta LifeScience SKU/CAT #: BL-4273PS
Catalog No.: BL-4273PS

Product Overview

Tag His
Host Species Human
Synonym Transcription Factor 4, Class B Basic Helix-Loop-HelixProtein 19, Immunoglobulin Transcription Factor 2, SL3-3 Enhancer Factor 2,BHLHb19, ITF-2, SEF-2, TCF-4, ITF2, SEF2, SEF2-1A, SEF2-1B, SEF2-1D, SEF2-1,FECD3, E2-2, PTHS.
Background Transcription Factor 4 (TCF4) acts as a transcription factor and takes part in the initiation of neuronal differentiation. TCF4 recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif primary identified in immunoglobulin enhancers. TCF4 is mainly expressed in pre-B-cells, even though it is present in other tissues as well.
Description TCF4 expressed in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 513a.a. (1-507a.a.) andhaving a molecular weight of 54.9kDa (Molecular size on SDS-PAGE will appear atapproximately 35-100kDa). TCF4 is expressed with a 6a.a. His tag atC-Terminus and purified by unique purification methods.
Source Sf9
AA Sequence MKFKQCRCSD TGLCCLDHEG KAEVYAPSAS TADYNRDSPG YPSSKPATSTFPSSFFMQDG HHSSDPWSSS SGMNQPGYAG MLGNSSHIPQ SSSYCSLHPH ERLSYPSHSS ADINSSLPPMSTFHRSGTNH YSTSSCTPPA NGTDSIMANR GSGAAGSSQT GDALGKALAS IYSPDHTNNS FSSNPSTPVG SPPSLSAGTA VWSRNGGQAS SSPNYEGPLH SLQSRIEDRLERLDDAIHVL RNHAVGPSTA MPGGHGDMHG IIGPSHNGAM GGLGSGYGTG LLSANRHSLM VGTHREDGVALRGSHSLLPN QVPVPQLPVQ SATSPDLNPP QDPYRGMPPG LQGQSVSSGS SEIKSDDEGD ENLQDTKSSE DKKLDDDKKDIKSITSNNDD EDLTPEQKAE REKERRMANN ARERLRVRDI NEAFKELGRM VQLHLKSDKP QTKLLILHQA VAVILSLEQQVRERNLNPKA ACLKRREEEK VSSEPPPLSL AGPHPGMGDA SNHMGQMHHH HHH.
Purity Greaterthan 85.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation TCF4 protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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