Recombinant Human TCblR Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0066NP
Recombinant Human TCblR Protein (Fc Tag)

Recombinant Human TCblR Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0066NP
Catalog No.: BL-0066NP

Product Overview

Tag Fc
Host Species Human
Accession Q9NPF0
Synonym TCblR CD320 antigen;8D6 antigen;FDC-signaling molecule 8D6;FDC-SM-8D6;Transcobalamin receptor;TCblR;CD320
Background CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
Description Recombinant Human Transcobalamin II Receptor is expressed by our Mammalian expression system and the target gene encoding Ser36-Val231 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Ser36-Val231
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human TCblR Protein was lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human TCblR protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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