Recombinant Human SUMO1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0345NP
Recombinant Human SUMO1 Protein (His Tag)

Recombinant Human SUMO1 Protein (His Tag)

Beta LifeScience SKU/CAT #: BL-0345NP
Catalog No.: BL-0345NP

Product Overview

Tag His
Host Species Human
Accession P63165
Synonym SUMO1 Small Ubiquitin-Related Modifier 1; SUMO-1; GAP-Modifying Protein 1; GMP1; SMT3 Homolog 3; Sentrin; Ubiquitin-Homology Domain Protein PIC1; Ubiquitin-Like Protein SMT3C; Smt3C; Ubiquitin-Like Protein UBL1; SUMO1; SMT3C; SMT3H3; UBL1
Background Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
Description Recombinant Human Small Ubiquitin-Related Modifier 1 is expressed by our E.coli expression system and the target gene encoding Met1-Val101 is expressed with a His tag at the N-terminus.
Source E.coli
AA Sequence Met1-Val101
Purity >90% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human SUMO1 Protein was lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.5 .
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human SUMO1 protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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