Recombinant Human STK36 Protein

Beta LifeScience SKU/CAT #: BL-0306SG
Recombinant Human STK36 Protein

Recombinant Human STK36 Protein

Beta LifeScience SKU/CAT #: BL-0306SG
Catalog No.: BL-0306SG

Product Overview

Tag GST
Host Species Human
Accession BC026158
Synonym FU, DKFZp434N0223
Background STK36 is a member of the serine/threonine kinase family and is similar to a protein which plays a key role in the Hedgehog signaling pathway. STK36 is a positive regulator of the GLI zinc-finger transcription factors and controls the activity of GLI1 and GLI2 by opposing the effect of SUFU (1). STK36 is highly expressed in fetal lung and adult testis (2). STK36 is a target for the treatment of gastrointestinal cancers since the Hedgehog signaling pathway is frequently activated in certain kinds of gastrointestinal cancers. Defects in the STK36 gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia.
Description Recombinant human STK36 (1-457) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 1-457
Molecular Weight ~87 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human STK36 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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