Recombinant Human SPRR1B Protein

Beta LifeScience SKU/CAT #: BL-4235PS
Recombinant Human SPRR1B Protein

Recombinant Human SPRR1B Protein

Beta LifeScience SKU/CAT #: BL-4235PS
Catalog No.: BL-4235PS

Product Overview

Tag His
Host Species Human
Synonym Cornifin-B, 14.9 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B, SPRR1, GADD33, CORNIFIN.
Background Small Proline-Rich Protein 1B (SPRR1B) is a keratinocyte protein which first appears in the cell cytosol, but eventually becomes cross-linked to membrane proteins by transglutaminase. SPRR1B is cross-linked to membrane proteins by transglutaminase leading to formation of an insoluble envelope. SPRR1B functions as both amine donor and acceptor in transglutaminase-mediated cross-linkage. SPRR1B is expressed in the course of differentiation in squamous tissues such as epidermis, esophagus, tongue or trachea.
Description SPRR1B Human Recombinant expressed in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 2-89) containing 97a.a. including a 9 a.a N-terminal His tag. The total molecular weight is 10.9kDa (calculated).
Source E.coli
AA Sequence MKHHHHHHAS SQQQKQPCTP PPQLQQQQVK QPCQPPPQEP CIPKTKEPCH PKVPEPCHPK VPEPCQPKVP EPCHPKVPEP CPSIVTPAPA QQKTKQK.
Purity >95.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation SPRR1B filtered (0.4 µm) and lyophilized from 0.5mg/ml in 0.05M phosphate buffer and 0.075M NaCl, pH 7.4.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
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