Recombinant Human SPINT2 Protein

Beta LifeScience SKU/CAT #: BL-4597PS
Recombinant Human SPINT2 Protein

Recombinant Human SPINT2 Protein

Beta LifeScience SKU/CAT #: BL-4597PS
Catalog No.: BL-4597PS

Product Overview

Tag His
Host Species Human
Synonym Serine Peptidase Inhibitor, Kunitz Type, 2, PlacentalBikunin, Hepatocyte Growth Factor Activator Inhibitor Type 2, Serine ProteaseInhibitor, Kunitz Type, 2, HAI-2, HAI2, Kop, Kunitz-Type Protease Inhibitor 2, Placental,Bikunin, DIAR3, PB, Kunitz-type protease inhibitor 2.
Background SPINT2 is a transmembrane protein acts as an inhibitor of HGF activator. SPINT2 inhibits plasmin, plasma and tissue kallikrein, and factor XIa. SPINT2 has two extracellular Kunitz domains that inhibit few serine proteases. SPINT2 is assumed tumor suppressor, mutations in SPINT2 leads to a congenital sodium diarrhea.
Description SPINT2 expressed in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 176a.a. (28-197 a.a.) andhaving a molecular weight of 20kDa. (Molecular size on SDS-PAGE will appear atapproximately 18-28kDa).SPINT2 is expressed with a 6a.a. His tag atC-Terminus and purified by unique purification methods.
Source Sf9
AA Sequence ADRERSIHDFCLVSKVVGRC RASMPRWWYN VTDGSCQLFV YGGCDGNSNN YLTKEECLKK CATVTENATG DLATSRNAADSSVPSAPRRQ DSEDHSSDMF NYEEYCTANA VTGPCRASFP RWYFDVERNS CNNFIYGGCR GNKNSYRSEEACMLRCFRQQ ENPPLPLGSK HHHHHH.
Purity >80.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation SPINT2 protein solution (0.2mg/ml) contains phosphatebuffered saline (pH 7.4) and 10% glycerol.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Recently viewed