Recombinant Human SETD1A (KMT2F) Protein

Beta LifeScience SKU/CAT #: BL-0296SG
Recombinant Human SETD1A (KMT2F) Protein

Recombinant Human SETD1A (KMT2F) Protein

Beta LifeScience SKU/CAT #: BL-0296SG
Catalog No.: BL-0296SG

Product Overview

Tag GST
Host Species Human
Accession NM_014712
Synonym SETD1A; KMT2F; Set1; Set1A
Background As a member of the mixed lineage leukemia (MLL) family of histone methyltransferase, it specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Description Recombinant human SETD1A (1418-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 1418a.a.-end
Molecular Weight 61 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human SETD1A (KMT2F) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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