Recombinant Human SETD1A (KMT2F) Protein
Beta LifeScience
SKU/CAT #: BL-0296SG
Recombinant Human SETD1A (KMT2F) Protein
Beta LifeScience
SKU/CAT #: BL-0296SG
Catalog No.: BL-0296SG
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | NM_014712 |
| Synonym | SETD1A; KMT2F; Set1; Set1A |
| Background | As a member of the mixed lineage leukemia (MLL) family of histone methyltransferase, it specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. |
| Description | Recombinant human SETD1A (1418-end) was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. |
| Source | Sf9 insect cells |
| AA Sequence | 1418a.a.-end |
| Molecular Weight | 61 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Human SETD1A (KMT2F) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
