Recombinant Human SEMA4D Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0086NP
Recombinant Human SEMA4D Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BL-0086NP
Catalog No.: BL-0086NP
Product Overview
| Tag | Fc |
| Host Species | Human |
| Accession | Q92854 |
| Synonym | SEMA4D Semaphorin-4D; A8;BB18; GR3; CD100. |
| Background | Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. |
| Description | Recombinant Human Semaphorin 4D is expressed by our Mammalian expression system and the target gene encoding Met22-Arg734 is expressed with a Fc tag at the C-terminus. |
| Source | Human Cells |
| AA Sequence | Met22-Arg734 |
| Purity | >95% as determined by reducing SDS-PAGE. |
| Endotoxin | <0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Recombinant Human SEMA4D Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Usage | For Research Use Only |
| Storage | Human SEMA4D protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
