Recombinant Human SEMA4D Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0086NP
Recombinant Human SEMA4D Protein (Fc Tag)

Recombinant Human SEMA4D Protein (Fc Tag)

Beta LifeScience SKU/CAT #: BL-0086NP
Catalog No.: BL-0086NP

Product Overview

Tag Fc
Host Species Human
Accession Q92854
Synonym SEMA4D Semaphorin-4D; A8;BB18; GR3; CD100.
Background Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
Description Recombinant Human Semaphorin 4D is expressed by our Mammalian expression system and the target gene encoding Met22-Arg734 is expressed with a Fc tag at the C-terminus.
Source Human Cells
AA Sequence Met22-Arg734
Purity >95% as determined by reducing SDS-PAGE.
Endotoxin <0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Recombinant Human SEMA4D Protein was lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Dissolve the lyophilized protein in distilled water.
Usage For Research Use Only
Storage Human SEMA4D protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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