Recombinant Human RAC2 Protein

Beta LifeScience SKU/CAT #: BL-4461PS
Recombinant Human RAC2 Protein

Recombinant Human RAC2 Protein

Beta LifeScience SKU/CAT #: BL-4461PS
Catalog No.: BL-4461PS

Product Overview

Tag N/A
Host Species Human
Synonym p21-Rac2, Small G protein, GX, RAC2, HSPC022, EN-7.
Background RAC2 is a small signaling G protein/GTPase which is part of the RAS superfamily of small GTP-binding proteins which regulate cell growth, actin cytoskeletal organization, cell proliferation, survival, cell cycle progression, gene transcription rgulation and the activation of protein kinases. RAC2 cycles between an active gtp-bound and inactive gdp-bound state. In active state, RAC2 binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 is involved in the regulation of the nadph oxidase.
Description Recombinant RAC2 expressed in E.Coli is a single, non-glycosylated polypeptide chain containing 419a.a. and having a molecular weight of 47 kDa. RAC2 is fused to GST and purified by conventional chromatography techniques.
Source E.coli
AA Sequence MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMQA IKCVVVGDGA VGKTCLLISY TTNAFPGEYI PTVFDNYSAN VMVDSKPVNL GLWDTAGQED YDRLRPLSYP QTDVFLICFS LVSPASYENV RAKWFPEVRH HCPSTPIILV GTKLDLRDDK DTIEKLKEKK LAPITYPQGL ALAKEIDSVK YLECSALTQR GLKTVFDEAI RAVLCPQPTR QQKRACSLL.
Purity >90.0% as determined by SDS-PAGE.
Endotoxin <1.0 EU per μg by the LAL method.
Formulation The RAC2 protein solution (1mg/ml) contains 1x PBS pH-7.4.
Stability Recombinant protein is stable for 12 months at -70°C
Usage For Research Use Only
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
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