Recombinant Human PRMT8 Protein

Beta LifeScience SKU/CAT #: BL-0214SG
Recombinant Human PRMT8 Protein

Recombinant Human PRMT8 Protein

Beta LifeScience SKU/CAT #: BL-0214SG
Catalog No.: BL-0214SG

Product Overview

Tag GST
Host Species Human
Accession BC022458
Synonym HRMT1L3, HRMT1L4
Background PRMT8 (protein arginine methyltransferase 8), an arginine methyltransferase that exhibits type I PRMT activity, catalyzing the formation of omega-NG-monomethylated and asymmetrically omega-NG, NG-dimethylated arginine residues. Its N-terminal end harbors a myristoylation motif, and the myristoylation results in its association with the plasma membrane. Unlike other members of PRMTs, it is largely expressed in the brain. It was also found that the N-terminal domain may function as an autoregulator that may be displaced by interaction with one or more physiological inducers.
Description Full-length recombinant human PRMT8 was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence Full Length
Molecular Weight 74 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human PRMT8 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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