Recombinant Human PRMT3 Protein
Beta LifeScience
SKU/CAT #: BL-0211SG
Recombinant Human PRMT3 Protein
Beta LifeScience
SKU/CAT #: BL-0211SG
Catalog No.: BL-0211SG
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | BC064831 |
| Synonym | HRMT1L3 |
| Background | PRMT3 is a protein arginine methyltransferase that catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (1). 40S ribosomal protein S2 is a physiological substrate of PRMT3 and PRMT3 regulates ribosome biosynthesis at a stage beyond pre-rRNA processing. DAL-1 (differentially expressed in adenocarcinoma of the lung)/4.1B is a tumor suppressor gene that can significantly inhibits PRMT3 methylation of cellular substrates (2). Modulation of post-translational methylation may be an important mechanism through which DAL-1/4.1B affects tumor cell growth. |
| Description | Recombinant full-length human PRMT3 was produced by baculovirus in Sf9 insect cells, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. |
| Source | Sf9 insect cells |
| AA Sequence | Full Length |
| Molecular Weight | ~97 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Human PRMT3 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
