Human PPP1R8 (Nuclear Inhibitor Of Protein Phosphatase 1) - Recombinant Protein
Beta LifeScience
SKU/CAT #: BLT-02358P
SDS-PAGE analysis of Human PPP1R8 (Nuclear Inhibitor Of Protein Phosphatase 1) - Recombinant Protein, CAT# BLT-02358P, showing >90% purity under 15% SDS-PAGE (Reduced)
Human PPP1R8 (Nuclear Inhibitor Of Protein Phosphatase 1) - Recombinant Protein
Beta LifeScience
SKU/CAT #: BLT-02358P
Regular price
$59500
$595.00
Sale price$54500
$545.00Save $50
/
Quantity Pricing
| Pack Size | Price (USD) |
|---|---|
| 500 µg | $1,375 |
| 1 mg | $2,245 |
For direct online orders, quantity pricing will be displayed in cart when you add 5x100ug or 10x100ug
Submit an inquiry or email inquiry@betalifesci.com for a customization request or bulk order quote.
Connect with us via the live chat in the bottom corner to receive immediate assistance.
Product Overview
| Product Name | Recombinant Human PPP1R8 Protein |
| Product Overview | This recombinant human PPP1R8 protein includes amino acids 1-351aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id | Q12972 |
| Recommended Name | Nuclear inhibitor of protein phosphatase 1 |
| Gene Name | PPP1R8 |
| Synonyms | Nuclear inhibitor of protein phosphatase 1, ARD-1, ARD1, NIPP-1, NIPP1, PRO2047. |
| Species | Human |
| Predicted Molecular Mass | 39.5 kDa |
| Expression System | E.coli |
| Expression Range | 1-351aa |
| Tag | N-6His |
| Purity | >90% |
| Formulation | Lyophilized |
| Buffer | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition | 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction | Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications | Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area | Signal Transduction |
| Target Function | Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.; Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3' to purines and pyrimidines in A+U-rich regions. It generates 5'-phosphate termini at the site of cleavage. This isoform does not inhibit PP-1. May be implicated in mRNA splicing. |
| Subcellular Location | Nucleus. Nucleus speckle. Note=Primarily, but not exclusively, nuclear.; [Isoform Gamma]: Cytoplasm. Note=Found mainly in the cytoplasm. |
| Tissue Specificity | Ubiquitously expressed, with highest levels in heart and skeletal muscle, followed by brain, placenta, lung, liver and pancreas. Less abundant in kidney. The concentration and ratio between isoforms is cell-type dependent. Isoform Alpha (>90%) and isoform |
![SDS-PAGE analysis of Human NDUFV1 (Nadh Dehydrogenase [Ubiquinone] Flavoprotein 1, Mitochondrial) - Recombinant Protein, CAT# BLT-08321P, showing >90% purity under 15% SDS-PAGE (Reduced)](http://www.betalifesci.com/cdn/shop/files/1ihmbkjr21vdmc6j_{width}x.jpg?v=1753363793)
