Recombinant Human Pdz Domain-Containing Protein 11 (PDZD11) Protein (His-SUMO)
Beta LifeScience
SKU/CAT #: BLC-09953P

Greater than 90% as determined by SDS-PAGE.
Recombinant Human Pdz Domain-Containing Protein 11 (PDZD11) Protein (His-SUMO)
Beta LifeScience
SKU/CAT #: BLC-09953P
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Human Pdz Domain-Containing Protein 11 (PDZD11) Protein (His-SUMO) is produced by our E.coli expression system. This is a full length protein. |
Purity | Greater than 90% as determined by SDS-PAGE. |
Uniprotkb | Q5EBL8 |
Target Symbol | PDZD11 |
Synonyms | 1810012H22Rik; 2310079D11Rik; 2700099C19Rik; AI854765; AIPP1; ATPase interacting PDZ protein; PDZ domain containing 11; PDZ domain-containing protein 11; PDZ11_HUMAN; PDZD11; PISP; RGD1560007; RP13-26D14.3; RP23-213F21.2 |
Species | Homo sapiens (Human) |
Expression System | E.coli |
Tag | N-6His-SUMO |
Target Protein Sequence | MDSRIPYDDYPVVFLPAYENPPAWIPPHERVHHPDYNNELTQFLPRTITLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFPYNYHRQKERTVH |
Expression Range | 1-140aa |
Protein Length | Full Length |
Mol. Weight | 32.1kDa |
Research Area | Cell Biology |
Form | Liquid or Lyophilized powder |
Buffer | Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Reconstitution | Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
Storage | 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Target Details
Target Function | Mediates docking of ADAM10 to zonula adherens by interacting with PLEKHA7 which is required for PLEKHA7 to interact with the ADAM10-binding protein TSPAN33. |
Subcellular Location | [Isoform 2]: Secreted.; [Isoform 1]: Cytoplasm. Cell junction, adherens junction. Cell membrane. |
Database References | |
Tissue Specificity | Widely expressed (at protein level). |
Gene Functions References
- PDZD11 forms a complex with nectin-1 and nectin-3, and its PDZ domain interacts directly with the PDZ-binding motif of nectin-1. PMID: 27044745
- PDZD11 is an interacting partner with sodium-dependent multivitamin transporter in intestinal epithelial cells and that this interaction affects SMVT function and cell biology. PMID: 21183659