Recombinant Human N-Acetylneuraminate 9-O-Acetyltransferase (CASD1) Protein (His-SUMO)
Beta LifeScience
SKU/CAT #: BLC-10131P

Greater than 90% as determined by SDS-PAGE.
Recombinant Human N-Acetylneuraminate 9-O-Acetyltransferase (CASD1) Protein (His-SUMO)
Beta LifeScience
SKU/CAT #: BLC-10131P
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Human N-Acetylneuraminate 9-O-Acetyltransferase (CASD1) Protein (His-SUMO) is produced by our E.coli expression system. This is a protein fragment. |
Purity | Greater than 90% as determined by SDS-PAGE. |
Uniprotkb | Q96PB1 |
Target Symbol | CASD1 |
Synonyms | CASD1; C7orf12; Nbla04196N-acetylneuraminate 9-O-acetyltransferase; EC 2.3.1.45; CAS1 domain-containing protein 1; Sialate O-acetyltransferase; SOAT |
Species | Homo sapiens (Human) |
Expression System | E.coli |
Tag | N-6His-SUMO |
Target Protein Sequence | ASRRYRGNDSCEYLLSSGRFLGEKVWQPHSCMMHKYKISEAKNCLVDKHIAFIGDSRIRQLFYSFVKIINPQFKEEGNKHENIPFEDKTASVKVDFLWHPEVNGSMKQCIKVWTEDSIAKPHVIVAGAATWSIKIHNGSSEALSQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLSENRKMITNEKIDAYNEAAVSILNSSTRNSKSNVKMFSVSKLIAQETIMESLDGLHLPESSRETTAMILMNVYCNKILKPVDGSCCQPRPPVTLIQ |
Expression Range | 39-313aa |
Protein Length | Partial |
Mol. Weight | 47.2kDa |
Research Area | Cell Biology |
Form | Liquid or Lyophilized powder |
Buffer | Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Reconstitution | Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
Storage | 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Target Details
Target Function | O-acetyltransferase that catalyzes 9-O-acetylation of sialic acids. Sialic acids are sugars at the reducing end of glycoproteins and glycolipids, and are involved in various processes such as cell-cell interactions, host-pathogen recognition. |
Subcellular Location | Golgi apparatus membrane; Multi-pass membrane protein. |
Protein Families | PC-esterase family, CASD1 subfamily |
Database References | |
Tissue Specificity | Highly expressed in peripheral B lymphocytes. |
Gene Functions References
- CASD1 is a sialate O-acetyltransferase and serves as key enzyme in the biosynthesis of 9-O-acetylated sialoglycans. PMID: 26169044
- human Cas1 protein is directly involved in O-acetylation of alpha2-8-linked sialic acids PMID: 20947662