Recombinant Human MPZL3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3406
Recombinant Human MPZL3 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-3406
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | NP_938016.1 |
Background | MPZL3 was essential for normal differentiation, acting downstream of p63, ZNF75, KLF4, and RCOR1, each of which bound near the MPZL3 gene and controlled its expression. MPZL3 protein localized to mitochondria, where it interacted with FDXR, which was itself also found to be essential for differentiation.Together, MPZL3 and FDXR increased reactive oxygen species (ROS) to drive epidermal differentiation. ROS-induced differentiation is dependent upon promotion of FDXR enzymatic activity by MPZL3. ROS induction by the MPZL3 and FDXR mitochondrial proteins is therefore essential for epidermal differentiation. |
Description | A DNA sequence encoding the human MPZL3 (NP_938016.1) (Met1-Ser158) was expressed with a His tag at the C-terminus. |
Source | HEK293 |
Predicted N Terminal | Leu 32 |
AA Sequence | Met1-Ser158 |
Molecular Weight | The recombinant human MPZL3 consists of 138 a.a. and predicts a molecular mass of 15.6 kDa. |
Purity | >95% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |