Recombinant Human MINK1 Protein

Beta LifeScience SKU/CAT #: BL-0279SG
Recombinant Human MINK1 Protein

Recombinant Human MINK1 Protein

Beta LifeScience SKU/CAT #: BL-0279SG
Catalog No.: BL-0279SG

Product Overview

Tag GST
Host Species Human
Accession NM_015716
Synonym B55; ZC3; MINK; YSK2; hMINK; MAP4K6; MGC21111; hMINKB
Background MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes, including cell morphology, cytoskeletal rearrangement, and survival (1). Overexpression of kinase-dead mutants of MINK1 leads to enhanced cell spreading, actin stress fiber formation, adhesion to extracellular matrix and decreased cell motility and invasion. MINK is activated after Ras induction via a mechanism involving reactive oxygen species and mediates stimulation of p38 MAPK downstream of the Raf/ERK pathway (2).
Description Recombinant human MINK1 (1-320) was produced by baculovirus in Sf9 insect cells using a N-terminual GST tag. This protein is purified with our unique purification methods.
Source Sf9 insect cells
AA Sequence 1-320a.a.
Molecular Weight ~61 kDa
Purity For specific purity information on a given lot, see related COA.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Bioactivity Active
Formulation Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.
Stability The recombinant protein is stable for up to 12 months at -70°C
Usage For Research Use Only
Storage Recombinant Human MINK1 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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