Recombinant Human MINK1 Protein
Beta LifeScience
SKU/CAT #: BL-0279SG
Recombinant Human MINK1 Protein
Beta LifeScience
SKU/CAT #: BL-0279SG
Catalog No.: BL-0279SG
Product Overview
| Tag | GST |
| Host Species | Human |
| Accession | NM_015716 |
| Synonym | B55; ZC3; MINK; YSK2; hMINK; MAP4K6; MGC21111; hMINKB |
| Background | MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes, including cell morphology, cytoskeletal rearrangement, and survival (1). Overexpression of kinase-dead mutants of MINK1 leads to enhanced cell spreading, actin stress fiber formation, adhesion to extracellular matrix and decreased cell motility and invasion. MINK is activated after Ras induction via a mechanism involving reactive oxygen species and mediates stimulation of p38 MAPK downstream of the Raf/ERK pathway (2). |
| Description | Recombinant human MINK1 (1-320) was produced by baculovirus in Sf9 insect cells using a N-terminual GST tag. This protein is purified with our unique purification methods. |
| Source | Sf9 insect cells |
| AA Sequence | 1-320a.a. |
| Molecular Weight | ~61 kDa |
| Purity | For specific purity information on a given lot, see related COA. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
| Bioactivity | Active |
| Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
| Stability | The recombinant protein is stable for up to 12 months at -70°C |
| Usage | For Research Use Only |
| Storage | Recombinant Human MINK1 Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
