Recombinant Human MEK4 (MAP2K4) Protein
Beta LifeScience
SKU/CAT #: BL-1150SG
Recombinant Human MEK4 (MAP2K4) Protein
Beta LifeScience
SKU/CAT #: BL-1150SG
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | GST |
Host Species | Human |
Accession | NM_003010 |
Synonym | MAP2K4, JNKK, MEK4, JNKK1, SERK1, MAPKK4, PRKMK4, SEK1 |
Background | MEK4 is a member of the mitogen-activated protein kinase family and is involved in the stress-activated protein kinase pathway where it phosphorylates c-Jun NH2-terminal kinase (1). MEK4 is part of a signaling system that is stimulated in the presence of stress to the cell (including chemotherapy), and it controls differentiation and programmed cell death (apoptosis). MEK4 is central component of signal transduction pathways induced by mitogens and stresses. MEK4 genetic inactivation has been observed in a subset of pancreatic carcinomas, implicating deregulation of the stress-activated protein kinase pathway in pancreatic carcinogenesis (2). |
Description | Recombinant human MEK4 (33-end) was produced in E. coli system, fused with a GST tag at N-terminus. This protein is purified with our unique purification methods. |
Source | E.coli |
AA Sequence | 33a.a.-end |
Molecular Weight | 63 kDa |
Purity | For specific purity information on a given lot, see related COA. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Formulation | Recombinant protein is supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol. |
Stability | The recombinant protein is stable for up to 12 months at -70°C |
Usage | For Research Use Only |
Storage | Recombinant Human MEK4 (MAP2K4) Protein should be stored should be stored at < -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |